Jaki, Thomas F.: search on Z-Library

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1

Estimation of pharmacokinetic parameters with the R package PK

Thomas Jaki, Martin J. Wolfsegger

Journal:

Pharmaceutical Statistics

Year:

2011

Language:

english

File:

PDF, 147 KB

english, 2011

2

A Bayesian adaptive design for clinical trials in rare diseases

Williamson, Faye, Jacko, Peter, Villar, Sofía S., Jaki, Thomas

Journal:

Computational Statistics & Data Analysis

Year:

2016

Language:

english

File:

PDF, 864 KB

english, 2016

3

Randomized dose-escalation designs for drug combination cancer trials with immunotherapy

Mozgunov, Pavel, Jaki, Thomas, Paoletti, Xavier

Journal:

Journal of Biopharmaceutical Statistics

Year:

2018

Language:

english

File:

PDF, 1.88 MB

english, 2018

4

Adaptive two-stage bioequivalence trials with early stopping and sample size re-estimation

Koenig, Franz, Wolfsegger, Martin, Jaki, Thomas, Schütz, Helmut, Wassmer, Gernot

Journal:

Year:

2015

Language:

english

File:

PDF, 285 KB

english, 2015

5

Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks

Dean, Natalie E., Gsell, Pierre-StÃ©phane, Brookmeyer, Ron, Crawford, Forrest W., Donnelly, Christl A., Ellenberg, Susan S., Fleming, Thomas R., Halloran, M. Elizabeth, Horby, Peter, Jaki, Thomas, Kra

Journal:

New England Journal of Medicine

Year:

2020

Language:

english

File:

PDF, 306 KB

english, 2020

6

A novel Phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer

John Whitehead, Helene Thygesen, Thomas Jaki, Scot Davies, Sarah Halford, Helen Turner, Natalie Cook, Duncan Jodrell

Journal:

Statistics in Medicine

Year:

2012

Language:

english

File:

PDF, 638 KB

english, 2012

7

Assessing goodnessâofâfit for evaluation of doseâproportionality

Wolfsegger, Martin J., Bauer, Alexander, Labes, Detlew, SchÃ¼tz, Helmut, Vonk, Richardus, Lang, Benjamin, Lehr, Stephan, Jaki, Thomas F., Engl, Werner, Hale, Michael D.

Journal:

Pharmaceutical Statistics

Year:

2020

File:

PDF, 1.15 MB

2020

8

Not Quite Normal: Consequences of Violating the Assumption of Normality in Regression Mixture Models

Van Horn, M. Lee, Smith, Jessalyn, Fagan, Abigail A., Jaki, Thomas, Feaster, Daniel J., Masyn, Katherine, Hawkins, J. David, Howe, George

Journal:

Structural Equation Modeling A Multidisciplinary Journal

Year:

2012

Language:

english

File:

PDF, 405 KB

english, 2012

9

Modeling Predictors of Latent Classes in Regression Mixture Models

Kim, Minjung, Vermunt, Jeroen, Bakk, Zsuzsa, Jaki, Thomas, Van Horn, M. Lee

Journal:

Structural Equation Modeling A Multidisciplinary Journal

Year:

2016

Language:

english

File:

PDF, 418 KB

english, 2016

10

Multiplicity: discussion points from the Statisticians in the Pharmaceutical Industry multiplicity expert group

Phillips, Alan, Fletcher, Chrissie, Atkinson, Gary, Channon, Eddie, Douiri, Abdel, Jaki, Thomas, Maca, Jeff, Morgan, David, Roger, James Henry, Terrill, Paul

Journal:

Pharmaceutical Statistics

Year:

2013

Language:

english

File:

PDF, 84 KB

english, 2013

11

Treatment selection in multi-arm, multi-stage clinical trials

Thomas Jaki,Dominic Magirr,Nigel Stallard

Journal:

Year:

2013

Language:

english

File:

PDF, 119 KB

english, 2013

12

Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: a case study

Jaki, Thomas, Wason, James M. S.

Journal:

BMC Cardiovascular Disorders

Year:

2018

Language:

english

File:

PDF, 946 KB

english, 2018

13

Subgroup identification in clinical trials via the predicted individual treatment effect

Ballarini, Nicolás M., Rosenkranz, Gerd K., Jaki, Thomas, König, Franz, Posch, Martin, Hubbard, Alan

Journal:

Year:

2018

Language:

english

File:

PDF, 870 KB

english, 2018

14

Dose-escalation strategies which use subgroup information

Cotterill, Amy, Jaki, Thomas

Journal:

Pharmaceutical Statistics

Year:

2018

Language:

english

File:

PDF, 900 KB

english, 2018

15

Using Multilevel Regression Mixture Models to Identify Level-1 Heterogeneity in Level-2 Effects

Van Horn, M. Lee, Feng, Yuling, Kim, Minjung, Lamont, Andrea, Feaster, Daniel, Jaki, Thomas

Journal:

Structural Equation Modeling A Multidisciplinary Journal

Year:

2015

Language:

english

File:

PDF, 178 KB

english, 2015

16

A comparison of phase I dose-finding designs in clinical trials with monotonicity assumption violation

Abbas, Rachid, Rossoni, Caroline, Jaki, Thomas, Paoletti, Xavier, Mozgunov, Pavel

Journal:

Clinical Trials

Year:

2020

File:

PDF, 536 KB

2020

17

The Effects of Sample Size on the Estimation of Regression Mixture Models

Jaki, Thomas, Kim, Minjung, Lamont, Andrea, George, Melissa, Chang, Chi, Feaster, Daniel, Van Horn, M. Lee

Journal:

Educational and Psychological Measurement

Year:

2018

Language:

english

File:

PDF, 419 KB

english, 2018

18

A hybrid method to estimate the minimum effective dose for monotone and non-monotone dose-response relationships

Wolfsegger, Martin J., Gutjahr, Georg, Engl, Werner, Jaki, Thomas

Journal:

Year:

2014

Language:

english

File:

PDF, 203 KB

english, 2014

19

Recording Lectures as a Service in a Service Course

Journal:

Journal of Statistics Education

Year:

2009

Language:

english

File:

PDF, 278 KB

english, 2009

20

Impact of Intensive Lifestyle Intervention on Neural Food Cue Reactivity: Action for Health in Diabetes Brain Ancillary Study

McDermott, Kathryn Demos, Williams, Samantha E., Espeland, Mark A., Erickson, Kirk, Neiberg, Rebecca, Wadden, Thomas A., Bryan, R. Nick, Desiderio, Lisa, Leckie, Regina L., Falconbridge, Lucy H., Jaki

Journal:

Year:

2019

Language:

english

File:

PDF, 528 KB

english, 2019

21

A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis

McWilliam, Stephen J., Rosala-Hallas, Anna, Jones, Ashley P., Shaw, Victoria, Greenhalf, William, Jaki, Thomas, Smyth, Alan R., Smyth, Rosalind L., Pirmohamed, Munir

Journal:

Scientific Reports

Year:

2020

Language:

english

File:

PDF, 1.16 MB

english, 2020

22

Non-compartmental estimation of pharmacokinetic parameters for flexible sampling designs

Thomas Jaki, Martin J. Wolfsegger

Journal:

Statistics in Medicine

Year:

2012

Language:

english

File:

PDF, 188 KB

english, 2012

23

Symmetric maximum kernel likelihood estimation

Jaki, Thomas, Webster West, R.

Journal:

Journal of Statistical Computation and Simulation

Year:

2011

Language:

english

File:

PDF, 300 KB

english, 2011

24

Authors' reply to Comments on ‘Estimation in AB/BA crossover trials with application to bioequivalence studies with incomplete and complete data designs”

Jaki, Thomas, Pallmann, Philip, Wolfsegger, Martin J.

Journal:

Statistics in Medicine

Year:

2013

Language:

english

File:

PDF, 47 KB

english, 2013

25

Analysing malaria drug trials on a per-individual or per-clone basis: a comparison of methods

Jaki, Thomas, Parry, Alice, Winter, Katherine, Hastings, Ian

Journal:

Statistics in Medicine

Year:

2013

Language:

english

File:

PDF, 567 KB

english, 2013

26

Simultaneous confidence regions for multivariate bioequivalence

Pallmann, Philip, Jaki, Thomas

Journal:

Statistics in Medicine

Year:

2017

Language:

english

File:

PDF, 2.60 MB

english, 2017

27

Recruitment progression rules for internal pilot studies monitoring recruitment

Hampson, Lisa, Williamson, Paula, Wilby, Martin, Jaki, Thomas

Journal:

Year:

2015

Language:

english

File:

PDF, 284 KB

english, 2015

28

A framework for prospectively defining progression rules for internal pilot studies monitoring recruitment

Hampson, Lisa V, Williamson, Paula R, Wilby, Martin J, Jaki, Thomas

Journal:

Statistical Methods in Medical Research

Year:

2017

Language:

english

File:

PDF, 367 KB

english, 2017

29

Instrumental variable estimation in semi-parametric additive hazards models

Brueckner, Matthias, Titman, Andrew, Jaki, Thomas

Journal:

Year:

2018

Language:

english

File:

PDF, 280 KB

english, 2018

30

Estimation in multi-arm two-stage trials with treatment selection and time-to-event endpoint

Brückner, Matthias, Titman, Andrew, Jaki, Thomas

Journal:

Statistics in Medicine

Year:

2017

Language:

english

File:

PDF, 722 KB

english, 2017

31

A comparison of stochastic programming methods for portfolio level decision-making

Graham, Emily, Jaki, Thomas, Harbron, Chris

Journal:

Journal of Biopharmaceutical Statistics

Year:

2019

File:

PDF, 2.33 MB

2019

32

Using a doseâfinding benchmark to quantify the loss incurred by dichotomization in Phase II doseâranging studies

Mozgunov, Pavel, Jaki, Thomas, Paoletti, Xavier

Journal:

Biometrical Journal

Year:

2020

File:

PDF, 310 KB

2020

33

The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design

Dimairo, Munyaradzi, Pallmann, Philip, Wason, James, Todd, Susan, Jaki, Thomas, Julious, Steven A, Mander, Adrian P, Weir, Christopher J, Koenig, Franz, Walton, Marc K, Nicholl, Jon P, Coates, Elizabe

Journal:

Year:

2020

File:

PDF, 818 KB

2020

34

Estimation of AUC from 0 to Infinity in Serial Sacrifice Designs

Martin Josef Wolfsegger, Thomas Jaki

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2005

Language:

english

File:

PDF, 142 KB

english, 2005

35

Principles of dose finding studies in cancer: a comparison of trial designs

Thomas Jaki, Sally Clive, Christopher J. Weir

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 291 KB

english, 2013

36

Planning multi-arm screening studies within the context of a drug development program

Wason, James M. S., Jaki, Thomas, Stallard, Nigel

Journal:

Statistics in Medicine

Year:

2013

Language:

english

File:

PDF, 157 KB

english, 2013

37

Recovering Independent Associations in Genetics: A Comparison

Sperrin, Matthew, Jaki, Thomas

Journal:

Journal of Computational Biology

Year:

2012

Language:

english

File:

PDF, 333 KB

english, 2012

38

Maximum Kernel Likelihood Estimation

Thomas Jaki and R. Webster West

Journal:

Journal of Computational and Graphical Statistics

Year:

2008

Language:

english

File:

PDF, 1.35 MB

english, 2008

39

Adaptive designs for phase II cross-over dose-finding trials using Bayesian model averaging

Simpson, Sarah, Hampson, Lisa, Jaki, Thomas, Jones, Byron

Journal:

Year:

2015

Language:

english

File:

PDF, 283 KB

english, 2015

40

Designing and evaluating dose-escalation studies made easy: The MoDEsT web app

Pallmann, Philip, Wan, Fang, Mander, Adrian P, Wheeler, Graham M, Yap, Christina, Clive, Sally, Hampson, Lisa V, Jaki, Thomas

Journal:

Clinical Trials

Year:

2019

File:

PDF, 2.28 MB

2019

41

Exposureâresponse modelling approaches for determining optimal dosing rules in children

Wadsworth, Ian, Hampson, Lisa V, Bornkamp, BjÃ¶rn, Jaki, Thomas

Journal:

Statistical Methods in Medical Research

Year:

2020

Language:

english

File:

PDF, 1.27 MB

english, 2020

42

Estimation of treatment effects following a sequential trial of multiple treatments

Whitehead, John, Desai, Yasin, Jaki, Thomas

Journal:

Statistics in Medicine

Year:

2020

File:

PDF, 1.11 MB

2020

43

Using regression mixture models with non-normal data: examining an ordered polytomous approach

George, Melissa R.W., Yang, Na, Van Horn, M. Lee, Smith, Jessalyn, Jaki, Thomas, Feaster, Daniel J., Masyn, Katherine, Howe, George

Journal:

Journal of Statistical Computation and Simulation

Year:

2013

Language:

english

File:

PDF, 359 KB

english, 2013

44

Clinical Drug Development in Epilepsy Revisited: A Proposal for a New Paradigm Streamlined Using Extrapolation

Wadsworth, Ian, Jaki, Thomas, Sills, Graeme J., Appleton, Richard, Cross, J. Helen, Marson, Anthony G., Martland, Tim, McLellan, Ailsa, Smith, Philip E. M., Pellock, John M., Hampson, Lisa V.

Journal:

Year:

2016

Language:

english

File:

PDF, 436 KB

english, 2016

45

Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of telmisartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on combination antiretroviral therapy

Pushpakom, Sudeep P, Taylor, Claire, Kolamunnage-Dona, Ruwanthi, Spowart, Catherine, Vora, Jiten, García-Fiñana, Marta, Kemp, Graham J, Whitehead, John, Jaki, Thomas, Khoo, Saye, Williamson, Paula, Pi

Journal:

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

46

Tilting the lasso by knowledge-based post-processing

Tharmaratnam, Kukatharmini, Sperrin, Matthew, Jaki, Thomas, Reppe, Sjur, Frigessi, Arnoldo

Journal:

BMC Bioinformatics

Year:

2016

Language:

english

File:

PDF, 466 KB

english, 2016

47

An information theoretic phase I-II design for molecularly targeted agents that does not require an assumption of monotonicity

Mozgunov, Pavel, Jaki, Thomas

Journal:

Journal of the Royal Statistical Society: Series C (Applied Statistics)

Year:

2018

Language:

english

File:

PDF, 710 KB

english, 2018

48

Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design

Dimairo, Munyaradzi, Coates, Elizabeth, Pallmann, Philip, Todd, Susan, Julious, Steven A., Jaki, Thomas, Wason, James, Mander, Adrian P., Weir, Christopher J., Koenig, Franz, Walton, Marc K., Biggs, K

Journal:

Year:

2018

Language:

english

File:

PDF, 1.59 MB

english, 2018

49

Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: a case study

Jaki, Thomas, Wason, James M. S.

Journal:

BMC Cardiovascular Disorders

Year:

2018

File:

PDF, 946 KB

2018

50

Impact of Intensive Lifestyle Intervention on Neural Food Cue Reactivity: Action for Health in Diabetes Brain Ancillary Study

McDermott, Kathryn Demos, Williams, Samantha E., Espeland, Mark A., Erickson, Kirk, Neiberg, Rebecca, Wadden, Thomas A., Bryan, R. Nick, Desiderio, Lisa, Leckie, Regina L., Falconbridge, Lucy H., Jaki

Journal:

Year:

2019

File:

PDF, 528 KB

2019

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